Seminoma

General:

Gross:

Microscopic: Uniform cells with abundant clear cytoplasm full of PAS+ glycogen, sharply outlined cell membranes, a large central nucleus with prominent nucleoli and clumped chromatin. The cells are arranged in nests outlined by lacy fibrous bands.

Staining:

• Positive: PLAP+, CD117+
• Negative: CD30-, CD45-
• Suggested panel:

(1)

Images:

Cases:

• Extra-gonadal seminoma in post renal transplant patient, possibly originating in donor tissue. Pending resolution/formal writeup.