Multiple Myeloma (plasma cell myeloma, multiple plasmacytomas)
General: Result from clonal expansion of immunoglobulin secreting, terminally differentiated B-cells. This secretory component may be termed the "M component" or monoclonal component, and may be seen prominently on serum &/or urine electrophoresis, also leading to terms such as monoclonal gammopathies, dysproteinemias, & paraproteinemias; however, these terms are considered nonspecific and may represent benign or malignant underlying causes.
Gross:
Microscopic:
Differential Diagnosis:
Stains:
- Positive:
- Negative:
- Suggested, focused panel:
((()))
Images:
Cases:
This site contains private study notes and is under construction, constant re-organization, and updating/correction. Although effort is made to ensure the accuracy of the contents, it should NOT be considered an authoritative medical reference. Thank you.